In vivo anti-virulence testing on commercial species

Testing on commercial species

The anti-disease properties of QS-disrupting products can be verified in different animal models:

• Gnotobiototic brine shrimp (Artemia) larvae
• Sea bass larvae (gnotobiotic)
• Tilapia
• Giant freshwater prawn (Macrobrachium rosenbergii)
• Whiteleg shrimp (Litopenaeus vannamei)
• Blue mussel (Mylitus edulis)

How

The anti-virulence effect of a product can be justified by monitoring the survival, the fitness (motility) and the pathogen load in the gut of the animals after challenging them with a pathogenic bacteria.